Artificial Heart

Next Generation Artificial Heart Project

Since 1995, we have been developing "Next Generation Artificial Heart" with National Institute of Advanced Industrial Science and Technology and Institute of Clinical Medicine in University of Tsukuba.
Now we are developing the artificial heart with noninvasive sensors, the sensorized and intelligent artificial heart called Smart Artificial Heart, in order to realize the safety treatment and the effective control for the patients.
Furthermore, to develop the bio-telemetry system for the long-term medical treatment with the artificial heart, we are developing the "Tsukuba Bio-Telemetry System", which can observe the condition of the patients and the driving condition of artificial heart from a remote place on-line.



Smart Artificial Heart and Bio-Telemetry System

Research Topics

Sensorized Aritificial Heart
To realize the safety treatment and effective control of artificial heart, we have been developing the artificial heart with noninvasive sensors and the sensorized artificial heart.
As the artificial heart contacts directly with the blood, the blood vessel and circulatory system of heart, the sensor system built into the artificial heart enables to measure the physiological conditions and artificial heart driving conditions noninvasively.
Reference:
"Development of Built-in-type and Noninvasive Sensor System for Smart
Artificial Heart(SAH)", ASAIO Journal, vol.49 (3), 265-270, 2003
Remote Monitoring System
To develop the bio-telemetry system for the long-term medical treatment with the artificial heart, it is important to observe the physiological condition and the driving condition of the artificial heart online.
In this research, we have been constructed the "Tsukuba Bio Telemetry System", which can observe the condition of the patients and the driving condition of artificial heart from a remote place online.
Reference:
"Development of Intelligent Wearable Management Server for Implantable Artificial Heart", Abstract of Artif Organs, 2003
"Tsukuba Remote Monitoring System for Continuous-Flow Artificial Heart",
Artif Organs, vol.27 (10), 897-906, 2003
Physiological Model
To develop an effective medical care and therapeutic control with an artificial heart, it is desired to apply not only the measured physiological data but also the unmeasured internal physiological data.
In this research, we have been constructed the physiological model andsome kinds of the parameter identification method to observe the time varying and unmeasured hemodynamics of internal human body.
Reference:
"Online Parameter Identification for Second Order Physiological Systemic
Circulation Model using Delta-Operator," Artif Organs, vol.26 (11), 967-970, 2002

"Resonant Frequency Control for the Artificial Heart using the online Parameter Identification", Artif Organs, vol.28(10), 2004, in press.
Noninvasive Thrombus Detection
In development of an artificial heart, thrombus formation is still serious problem. However, there is no effective means to detect a thrombus. An optical measurement method is one of the best approaches which realize noninvasive thrombus detection.
The purpose of this research is to develop the nonivasive thrombus detection method using NIR (Near Infra-Red) laser, and to apply the method to clinical use.
Reference:
"Development and Clinical Application of the Noninvasive Thrombus Detecting Method by NIR Laser", Proceeding of IEEE EMBS-BMES, 1807-1808, 2002